Popular Lottery Games with Massive Jackpots 1. **Powerball**: This American lottery game is known for its enormous jackpots, often exceeding hundreds of millions. Players choose five numbers from a set range, plus a Powerball number. 2. **Mega Millions**: Similar to Powerball, Mega Millions has become one of the leading games in the United States, featuring sky-high jackpots. Players select five numbers from one set and a Mega Ball from another.